Lance Leopold Selected Research

Ligands

1/2019

Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma.

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Lance Leopold Research Topics

Disease

8	Neoplasms (Cancer) 01/2022 - 03/2010
6	Prostatic Neoplasms (Prostate Cancer) 12/2014 - 05/2009
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2020 - 03/2010
2	Fatigue 01/2022 - 01/2017
2	Pruritus (Itching) 01/2019 - 01/2017
2	Exanthema (Rash) 01/2019 - 01/2017
2	Anemia 12/2015 - 10/2013
2	Neutropenia 12/2012 - 04/2011
1	Fever (Fevers) 01/2022
1	Vomiting 01/2022
1	Nausea 01/2022
1	Diarrhea 01/2022
1	Aseptic Meningitis 01/2022
1	Rhabdomyolysis 01/2021
1	Hyponatremia 10/2020
1	Hypotension (Low Blood Pressure) 10/2020
1	Dehydration (Water Stress) 10/2020
1	Autoimmune Diseases of the Nervous System 10/2020
1	Hypothyroidism 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Carcinoma (Carcinomatosis) 01/2017
1	Ovarian Neoplasms (Ovarian Cancer) 01/2017
1	Ovarian Epithelial Carcinoma 01/2017
1	Fallopian Tube Neoplasms 01/2017
1	Disease Progression 12/2015
1	Inflammation (Inflammations) 12/2015
1	Pancreatic Neoplasms (Pancreatic Cancer) 12/2015
1	Pain (Aches) 11/2013
1	Primary Myelofibrosis (Myelosclerosis) 10/2013
1	Thrombocytopenia (Thrombopenia) 10/2013
1	Headache (Headaches) 04/2011
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2010
1	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 03/2010
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 06/2008
1	B-Cell Lymphoma (Lymphoma, B Cell) 06/2008
1	Lymphoma (Lymphomas) 06/2008
1	Multiple Myeloma 06/2008

Drug/Important Bio-Agent (IBA)

8	epacadostatIBA 01/2022 - 01/2017
6	Docetaxel (Taxotere)FDA Link 11/2013 - 05/2009
5	gossypol acetic acidIBA 12/2012 - 06/2008
4	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2010
2	pembrolizumabIBA 01/2021 - 11/2018
2	EnzymesIBA 11/2018 - 01/2017
2	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 11/2018 - 01/2017
2	C-Reactive ProteinIBA 12/2015 - 12/2012
2	ruxolitinibIBA 12/2015 - 10/2013
2	Pharmaceutical PreparationsIBA 12/2014 - 06/2008
2	Prostate-Specific Antigen (Semenogelase)IBA 11/2013 - 12/2012
2	AndrogensIBA 11/2013 - 05/2009
2	Prednisone (Sone)FDA LinkGeneric 12/2012 - 02/2012
2	ErbB Receptors (EGF Receptor)IBA 04/2011 - 03/2010
1	itacitinibIBA 01/2022
1	parsaclisibIBA 01/2022
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	atezolizumabIBA 10/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2019
1	IpilimumabIBA 01/2019
1	Alanine Transaminase (SGPT)IBA 01/2019
1	LigandsIBA 01/2019
1	Programmed Cell Death 1 ReceptorIBA 01/2019
1	Tamoxifen FDA LinkGeneric 01/2017
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2017
1	Janus KinasesIBA 12/2015
1	Gemcitabine FDA Link 12/2015
1	Capecitabine (Xeloda)FDA Link 12/2015
1	Ketoconazole (Nizoral)FDA LinkGeneric 11/2013
1	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 11/2013
1	Abiraterone AcetateIBA 11/2013
1	Erythropoietin FDA Link 10/2013
1	Thrombopoietin (c-mpl Ligand)IBA 10/2013
1	Janus Kinase 1IBA 10/2013
1	Complement System Proteins (Complement)IBA 12/2012
1	Inhibitor of Apoptosis ProteinsIBA 04/2011
1	N- benzhydryl- 5- (2- (methylamino)propanamido)- 3- (3- methylbutanoyl)- 6- oxodecahydropyrrolo(1,2- a)(1,5)diazocine- 8- carboxamideIBA 04/2011
1	Topotecan (Hycamtin)FDA LinkGeneric 10/2010
1	Lapatinib (GW572016)FDA Link 03/2010
1	Tyrosine Kinase InhibitorsIBA 03/2010
1	Therapeutic UsesIBA 06/2008
1	carfilzomibIBA 06/2008
1	4-hydroxycyclophosphamideIBA 06/2008
1	Cytotoxins (Cytolysins)IBA 06/2008
1	Etoposide (VP 16)FDA LinkGeneric 06/2008
1	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2008

Therapy/Procedure

6	Drug Therapy (Chemotherapy) 01/2017 - 05/2009
5	Therapeutics 01/2017 - 04/2011
5	Castration 12/2014 - 02/2012
1	Immunotherapy 01/2017
1	Drug Tapering 10/2013